Applied Bioinformatics Group


A   A   A
Sections

Skip to content. | Skip to navigation

Nora C Toussaint

2012 -

Postdoctoral researcher in the Lucille Castori Center for Microbes, Inflammation & Cancer, Memorial Sloan-Kettering Cancer Center, New York, NY, U.S.A.

2011

Postdoctoral researcher in the Applied Bioinformatics group of Oliver Kohlbacher, Center for Bioinformatics, University of Tübingen, Germany 

2011

PhD thesis New approaches to in silico design of epitope-based vaccines at the Applied Bioinformatics group of Oliver Kohlbacher, Center for Bioinformatics, University of Tübingen, Germany

03/2010

Visiting researcher in the group of Yoram Louzoun at Bar-Ilan University, Ramat Gan, Israel

09/2009 - 11/2009

Visiting researcher in the Life Sciences group (leader: Gunnar W. Klau) at the CWI in Amsterdam, The Netherlands

2005 - 2011

PhD student/Research assistant in the Applied Bioinformatics group of Oliver Kohlbacher, Center for Bioinformatics, University of Tübingen, Germany

2005

Diploma thesis Counter-example guided abstraction refinement in high level petrinets at the Division for Theory of Programming, Department of Computer Science, Humboldt University, Berlin, Germany 

 

Research Interests:

  • Computational Immunology with focus on
  • Structural Bioinformatics with focus on protein design/structure prediction, more precisely side chain placement
 

Publications:

 
Toussaint, NC (2011).
PhD thesis, Universität Tübingen.

Toussaint, NC, Maman, Y, Kohlbacher, O, and Louzoun, Y (2011).
Vaccine, 29(47):8745-8753.
 
Toussaint, NC, Feldhahn, M, Ziehm, M, Stevanovic, S, and Kohlbacher, O (2011). 
Proc. ICIW 2011.
 
Canzar, S, Toussaint, NC, and Klau, GW (2011).
Optimization Letters, 1-14.
 
Hildebrandt, A, Dehof, AK, Rurainski, A, Bertsch, A, Schumann, M, Toussaint, NC, Moll, A, Stockel, D, Nickels, S, Mueller, SC, Lenhof, H-P, and Kohlbacher, O (2010).
BMC Bioinformatics, 11:531.
 

Toussaint, NC, Widmer, C, Kohlbacher, O, and Rätsch, G (2010). 
Exploiting Physico-Chemical Properties in String Kernels 
BMC Bioinformatics, 11(Suppl 8):S7.

Widmer, C, Altun, Y, Toussaint, NC, and Rätsch, G (2010). 
Inferring Latent Task Structure for Multi-Task Learning via Multiple Kernel Learning 
BMC Bioinformatics, 11(Suppl 8):S5.

Widmer, C, Toussaint, NC, Altun, Y, Kohlbacher, O, and Rätsch, G (2010). 
Novel Machine Learning Methods for MHC Class I Binding Prediction 
In: Pattern Recognition in Bioinformatics 5th IAPR International Conference, PRIB 2010, Nijmegen, The Netherlands, September 22-24, 2010. Proceedings, ed. by Tjeerd M.H. Dijkstra, Evgeni Tsivtsivadze, Elena Marchiori and Tom Heskes, vol. 6282, pp. 98-109, Springer. Lecture Notes in Computer Sciences.

Toussaint, NC and Kohlbacher, O (2009).
Nucl. Acids Res. 37:W617-22.
 
Toussaint, NC and Kohlbacher, O (2009).
Expert Opinion on Drug Discovery, 4(10):1047-1060.

Toussaint, NC, Dönnes, P, and Kohlbacher, O (2008).
PLoS Comput. Biol., 4(12):e1000246.
 

Conference & Workshop Papers/Presentations:

 
Toussaint, NC, Feldhahn, M, Ziehm, M, Stevanovic, S, and Kohlbacher, O (2011). 
2nd Immunoinformatics and Computational Immunology Workshop (ICIW 2011), Chicago, IL, U.S.A., August 1-3, 2011.
 
Canzar, SToussaint, NC, and Klau, GW (2011).
10th International Symposium on Experimental Algorithms, Kolimpari Chania, Greece, May 5-7, 2011. 

Widmer, CToussaint, NC, Altun, Y, and Rätsch, G (2010).
Multitask Multiple Kernel Learning (MT-MKL)
NIPS workshop on New Directions in Multiple Kernel Learning, Whistler, B.C., Canada, December 11, 2010. 
 
Widmer, CToussaint, NC, Altun, Y, Kohlbacher, O, and Rätsch, G (2010). 
Novel Machine Learning Methods for MHC Class I Binding Prediction
5th IAPR International Conference, PRIB 2010, Nijmegen, The Netherlands, September 22-24, 2010.
 
Toussaint, NC, Kohlbacher, O, and Rätsch, G (2009). 
Exploiting Physico-Chemical Properties in String Kernels
NIPS workshop on Machine Learning in Computational Biology, Whistler, B.C., Canada, December 10, 2009.
 
Toussaint, NC, Dönnes, P, and Kohlbacher, O (2009).
A Mathematical Framework for the Selection of an Optimal Set of Peptides for Epitope-Based Vaccines
ISMB/ECCB 2009 Highlights Track, Stockholm, Sweden, June 27 - July 2, 2009.
 

Talks:

  • Talk on T-Cell Epitope Prediction Based on Self-Tolerance at the 2nd Immunoinformatics and Computational Immunology Workshop, Chicago, IL, USA, on August 1, 2011.
  • Talk on A Mathematical Framework for the Selection of an Optimal Set of Peptides for Epitope-Based Vaccines at the Louzoun Lab, Bar-Ilan University, Israel, on March 14, 2010.
  • Talk on Exploiting Physico-Chemical Properties in String Kernels at the NIPS Workshop on Machine Learning in Computational Biology, Whistler, B.C., Canada, on December 11, 2009. Available online.
  • Talk on A Mathematical Framework for the Selection of an Optimal Set of Peptides for Epitope-Based Vaccines in the CWI-NISB Life Sciences Seminar at the CWI, Amsterdam, NL on September 4, 2009.
  • Talk on Combinatorial Optimization in Rational Vaccine Design at Tübinger Bioinformatik Tag, Center for Bioinformatics, Tübingen, Germany on April 24, 2009.

 

Latest content created by this user

Article Reference
Universal peptide vaccines – optimal peptide vaccine based on viral sequence conservation Aug 08, 2011
An exact algorithm for side-chain placement in protein design Mar 11, 2011
Inferring Latent Task Structure for Multi-Task Learning via Multiple Kernel Learning Jul 08, 2010
Exploiting Physico-Chemical Properties in String Kernels Jul 08, 2010
Page
ABi Breakfast Oct 21, 2009
Computational Immunomics (BIOINF 3360) Sep 08, 2009
Amino Acid String Kernels Sep 08, 2009
File
Daten für das Projekt T-Zell-Reaktivität Jun 05, 2012
Daten für das Projekt MHC-II Jun 05, 2012
Daten für das Projekt MHC-I Jun 05, 2012
report_template.tgz Jun 05, 2012
CI_SS11_10_SystemsImmuno_3up.pdf Jun 20, 2011
Folder
SS 2011 Feb 05, 2011
data_leslie May 31, 2010
data_iedb May 31, 2010
data_weston May 31, 2010
Uebung12 Jan 28, 2010
Inproceedings Reference
Novel Machine Learning Methods for MHC Class I Binding Prediction Jul 08, 2010
All content created by Nora C Toussaint…